World number one Andy Murray will need to keep his guard up when he takes on rising star Karen Khachanov for a spot in the last eight with the Russian having already caused two upsets on his French Open debut.
The 21-year-old, ranked 53rd in the world, eliminated 13th-seed Tomas Berdych in round two before beating big-serving John Isner, seeded 21st, in four sets.
Murray’s match on Court Philippe Chatrier, however, is not the highlight for the local fans, with Frenchman Gael Monfils taking on third-seed Stanlisas Wawrinka in their fourth round clash.
Monfils, a semi-finalist in 2008, reached the last 16 after fellow countryman Richard Gasquet retired due to a thigh injury midway through the third set.
Second seed Karolina Pliskova faces Paraguay’s Veronica Cepede Royg for a place in the last eight.